SCIENTIFIC NAME(S):Cucurbita pepo L. (pumpkin or pepo), c.maxima Duchesne (autumn squash), C. moschata Poir. (crookneck squash) Family: Cucurbitaceae
History
The seeds of several species of cucurbita have been used in traditional medicine for centuries. They have been used to immobilize and aid in the expulsion of intestinal worms and parasites. Traditionally, the seeds of Cucurbita species are ingested after grinding or as a tea. The amount of seeds that can exert a pharmacologic effect appears to vary by species, from as few as 50 g to more than 500 g. These are usually taken in several divided doses. Some cultures suggest eating small amounts of the seeds on a daily basis as a prophylactic against worm infections. The seeds also have been used in the treatment of prostate gland disorders.
Botany :- The members of this genus are plants that develop long vine-like stems that produce large edible fruits. The large, yellow flowers are eaten in some Mediterranean cultures; whereas, the fruits are eaten worldwide. Many cultivated varieties can be found throughout the world.
Uses of Cucurbita
Squashes, pumpkins, and other fruits of this family are consumed throughout the world. Flowers and seeds of some species are eaten. Seeds of some species are a traditional vermifuge. Also, components of some seeds may be useful in treating prostatic disorders.
Side Effects of Cucurbita
Severe toxicity has not been reported with the use of cucurbita extracts.
Dosage
Pumpkin seed oil extracts standardized for fatty acid content have been used in BPH trials. Men with BPH have used 160 mg three times per day with meals. Approximately 5-10 grams per day of pumpkin seeds may be needed for kidney stone prevention. 16 As a treatment for parasites, 200-400 grams are ground and taken with milk and honey, followed by castor oil two hours later. This treatment, however, should not be attempted unless under medical supervision.
Toxicology
Severe toxicity has not been reported with the use of cucurbita extracts. In a 53-patient, randomized, double-blind trial, no side effects from C. pepo were noted, Ingestion of C. maxima seeds by rats and pigs over a 4-week period resulted in no changes in glucose, urea, creatinine, liver enzymes, blood counts, etc. One report on C. moschata describes dermatitis.
